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The published research describes GHK-Cu's biological footprint as involving copper-dependent extracellular matrix processes (notably through the copper-dependent enzyme lysyl oxidase, which cross-links collagen and elastin), broad effects on gene expression characterized in transcriptomic studies, antioxidant and redox-related effects connected to copper biochemistry, and effects in wound-healing and tissue-repair research models

Cochrane Database Syst Rev 2006