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Observed Side Effects (From Clinical Trials) In the Lancet 2021 Phase 2 trial (n=706), at the highest 4.5 mg/week dose, 88% of participants reported at least one side effect and 63% reported a GI-specific event

Several other next-generation medications are also in development, each approaching weight management from different angles: Retatrutide is a new medication from Eli Lilly in trials that targets three hormones that control appetite and metabolism

It also inhibited tumor development in other parts of the intestine (6)