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Who should avoid IV Drip Therapy or require medical clearance first
Excessive pyroptosis leads to rapid rupture of the plasma membrane and the excessive release of proinflammatory cytokines and chemokines, which results in neuroinflammation that triggers a cascade of secondary injuries culminating in neuronal death
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These pathways not only preserve proteome integrity but also offer powerful therapeutic opportunities, as demonstrated by the emergence of proteasome inhibitors, autophagy modulators, and molecular chaperone-targeting agents in clinical medicine (Tables 1 and 2)
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