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Dietary supplements as a category generally don't undergo the FDA's drug-style premarket approval process for efficacy

Each bag contains 30 servings, providing a 1-month supply

Constipation Advise patients of the potential for severe constipation, including management instructions and when to seek medical attention (see ADVERSE REACTIONS and CLINICAL PHARMACOLOGY)

The overall objectives of the IPCS are to establish the scientific basis for assessment of the risk to human health and the environment from exposure to chemicals, through international peer review processes, as a prerequisite for the promotion of chemical safety, and to provide technical assistance in strengthening national capacities for the sound management of chemicals