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In contrast, a number of patients with lipodystrophy show hypertension in the leptin-deficient state [263, 264]

These findings highlight its significant potential as an immunomodulator for the treatment of allergic inflammation

The crucial role of glutamine in macrophages has been emphasized through early animal experiments, which have unveiled its irreplaceable involvement in cytokine generation, including prominent players like IL-1, IL-6, and tumour necrosis factor (TNF)- [124]

Current research suggests that a varied diet including sulfur-rich vegetables, fresh produce, and quality protein sources may help provide dietary glutathione and supporting nutrients