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Understanding what to expect, and knowing that support is available, can make treatment feel far more manageable

4 Discussion The present meta-analysis, incorporating 93 randomized controlled trials with over 1.85 million participants, provides the most comprehensive synthesis to date of the relationship between GLP-1 receptor agonists (GLP-1 RAs) and gastrointestinal (GI) cancer risk

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The most frequently reported cardiovascular risk factors were hypertension and dyslipidemia (4,627 (73.9%) participants had hypertension and 4,237 (67.7%) participants had dyslipidemia) (Supplementary Table 2)