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doi: 10.3389/fnmol.2025.1549366 Received 21 December 2024 Accepted 12 March 2025 Published 07 April 2025 Volume 18 - 2025 Edited by Inigo Ruiz de Azua, Johannes Gutenberg University Mainz, Germany Reviewed by Beatrice Ferrari, San Matteo Hospital Foundation (IRCCS), Italy Ken-ichiro Nakajima, Nagoya University, Japan Keisuke Ito, University of Shizuoka, Japan Updates Copyright 2025 Shiimura, Kojima and Sato

Clinical studies have tested doses up to 1000 mg or even 2000 mg daily of NR and found them to be well-tolerated with no serious adverse effects

Arch Pediatr Adolesc Med (2010) 164:81723

This is even true of our vitamin D3 source (sustainable, organic algae), which is unique to find in a multivitamin as most multis source D3 from lanolin, which is derived from sheeps wool