dizzy from tirzepatide reduces food intake and appetite, and affects brain functioning, more than placebo and liraglutide Tirzepatide (Zepbound) for weight loss

human C-cells express substantially lower levels of these same receptors Downstream signaling: Cellular responses differ between species C-cell biology: Rodent C-cells are inherently more prone to proliferation than human C-cells What the Warning Is, and Is Not Does advise against use in MTC/MEN2 patients Does NOT prove GLP-1 RAs causes MTC in humans whatsoever Does NOT apply to differentiated thyroid cancers of any type in any way In Summary: The warning exists because rodents developed C-cell tumors

But the blood work signal cannot be ignored

Additionally, certain medications (including some antipsychotics, antidepressants, and corticosteroids) and endocrine conditions can contribute to increased appetite and food preoccupation

Science 373 , eabd2893 (2021)