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The authors claim that nicotine seems to uncouple mitochondrial respiration via uncoupling protein 1 (UCP1) which consequently up-regulated BAT thermogenesis and significantly reduced bodyweight of MSG obese mice without affecting food intake" PubMed Central (PMC) Mitochondria as a possible target for nicotine action Mitochondria are multifunctional and dynamic organelles deeply integrated into cellular physiology and metabolism
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Garcia-Martinez JM, Alessi DR
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Research shows slu pp 332 is a novel agonist of the nuclear receptor REV-ERB, a key player in circadian rhythms and metabolic homeostasis
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doi: 10.1136/emj.2004.020693 [PubMed] 24286945 Alsahli M, Gerich JE
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