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Researchers originally developed it because they noticed that this particular region of growth hormone seemed responsible for its fat-metabolizing properties, without the growth-promoting or blood sugar effects that make full-length growth hormone problematic for weight management

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Nikolaou et al., 2013)

A few things to note here: The accuracy 5 days before the missed period is only 76%, and then it goes up to 96% 4 days before, and then 99% for the remaining days as you get closer to your period So its possible to have false negatives if youre testing too early, especially if you are off even by a day or two in your estimate of when youd expect your period False positives, on the other hand, are exceedingly rare - if you see even a faint line, you are almost certainly pregnant Early detection tests are expensive