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The absence of a placebo group may limit causal inference regarding the effects of GLP-1RAs on nicotine dependence and smoking-related outcomes

Men and those with musculoskeletal pain showed the steepest physical activity decline

By stimulating glucose-dependent insulin secretion and suppressing glucagon production, they are a cornerstone of the treatment of type 2 diabetes (DM2), particularly in patients with a higher risk of cardiovascular disease ( This narrative review describes the complex interplay between GLP-1 signalling and intestinal inflammation, highlighting both the potential benefits and limitations of GLP1 RAs in IBD management, with a particular focus on their promising role in selected obese IBD patients