People experiencing constipation on semaglutide or constipation on tirzepatide may find that butyrate-producing bacteria like Clostridium butyricum support bowel regularity through improved colonocyte function and motility
However, this anecdotal evidence is insufficient to establish causality
Whats more, its demographic analysis showed significant differences between the GLP-1 RA and comparator groups in factors such as age, HbA1c, body weight, BMI, duration of diabetes, sex, race, and so on, suggesting that the effect of GLP-1RAs on DR is yet controversial and that it may vary based on the specific GLP-1RA used, as well as the patients demographic and clinical characteristics
Postponing GLP-1 RAs before endoscopic intervention or surgery may hinder diabetes management and increase cancellation rates without significant advantages