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Why it's included Included for its role in supporting fat metabolism and energy production

Research published in the British Journal of Pharmacology demonstrated that molecular conjugation of B12 (specifically the corrin ring structure found in cyanocobalamin) with GLP-1 receptor agonists produced a compound that was not as readily absorbed into the brainstem areas responsible for triggering nausea

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As all cells in the body require cobalamin for single carbon metabolism, it has been hypothesized that cobalamin deficiency may actually contribute to the clinical signs and manifestations of gastrointestinal disease in some patients