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In CIRI, SLC25A4 and SLC25A5 lactylation increased, whereas VDAC1 lactylation decreased, linking lactylation to Ca 2+ dysregulation, mitochondrial impairment, and neuronal death

Kuceki, Wambier et al

Our results concluded that i) intracellular GSH is associated with antibiotic susceptibility, ii) extracellular GSH exhibited antibacterial activity regardless of antibiotic susceptibility and resistance, iii) the antibacterial activity of GSH synergistically enhanced susceptibility of conventional antibiotics, and iv) GSH-mediated acidity was partially associated with the antibacterial activity of GSH

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