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has developed PEGylated liposomes modified with BV2 microglial cell membranes (hFGF-21@BCM-LIP), enabling targeted delivery of liver-derived FGF-21 to AD pathological microenvironments via subcutaneous injection [99]

Diversity between the systems appears to have evolved through use of novel proteins, and matching of protein components between translocation machineries 8

Visceral fat is also linked to insulin-like growth factor signalling, inflammation and impaired immune surveillance, mechanisms that may help explain associations between visceral fat and certain cancers

But in practice, these two compounds produce completely different outcomes, work through fundamentally different mechanisms, and carry very different risk profiles