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According to results from the REDEFINE-4 trial, patients treated with CagriSema achieved an average weight reduction of approximately 23% after 84 weeks , a significant outcome in the field of obesity medicine

Fifth, regulatory and reimbursement varies across countries and regions, affecting its widespread implementation (148)

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When combined, these overlapping side effect profiles may worsen GI tolerability, particularly during the dose escalation phase when tirzepatide GI effects are already at their peak