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This is a promising line of research which could potentially increase the types of therapies we have available to us to help manage heart attack patients. Heart disease is the MNT also spoke with Andrew Adelsheimer, MD, a cardiologist at Atlantic Health, who commented that his first reaction was that this is an elegant mechanistic study that uses an animal model to discover the potential cardioprotective effect of GLP-1

Extending the exposure lag from 3 to 6 months yielded materially similar estimates ( Supplementary Table 3 )

In PIONEER 1 and 9 where semaglutide was used as monotherapy, patients were previously treated with diet and exercise, or an OAD (in PIONEER 9) that required a wash-out period

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