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The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects

Combination therapy should be approached with clinical discretion, and patients should be advised to avoid alcohol during treatment

Safety Profile Varies by Treatment Intensity: Adverse event rates increased with treatment complexity, with the triplet therapy showing higher discontinuation and severe treatment-emergent adverse event rates, though no direct link to treatment-related deaths was established

When will I start to see results