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Therefore, while Ca 2 signaling is central to plant adaptation, the complexity of its encoding and decoding mechanisms suggests that several critical processes remain to be elucidated

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For example, DPP-IV inhibitors have been shown to promote beta-cell survival and function, characterized as augmented GSIS, in islets of non-diabetic and T2DM human donors (113, 114), demonstrating that ligands of DPP-IV enzymatic activity that function in a similar capacity to alpha-cell-derived proglucagon ligands are both present and active in isolated islets