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Subjects participating in clinical trials can reduce gastrointestinal-related side effects by: Increasing fibre intake Incorporating foods rich in probiotics, such as yoghurt, kefir, and sauerkraut Staying hydrated Consuming smaller, more frequent meals Who Should Use Retatrutide

GLP-1 Tirzepatide Improves Heart Health in Obesity-Related HFpEF: Key Findings from the CMR Substudy of the SUMMIT Trial Since the 1990s, the incidence of heart failure with preserved ejection fraction (HFpEF) has risen, especially among patients with obesity

The GLP-1 receptor component is hypothesised to play a significant role in the observed rise in heart rate

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