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Primary Care Guidelines for B12 and Folate Testing Indications for B12 and Folate Testing No need to check B12 levels in patient on parenteral B12 treatment (they will always be high) There is no indication to check GPA or INF purely because of family history of autoimmune disease or hypothyroidism Care should be taken when prescribing folic acid alone If folic acid is given to a patient who is actually b12 deficient, this may precipitate irreversible neurological complications References 1

Hydroxocobalamin reduced whole blood cyanide concentrations by 50%, and two weeks after exposure and treatment, 100% of dogs in the 150 mg/kg treated group survived compared to 79% in the 75 mg/kg group and only 18% in the vehicle treated group (Borron et al., 2006)

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Internal stability improves under a reinforced lining structure