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Safety through Week 52 (CHRONOS) In the DUPIXENT with concomitant TCS trial (CHRONOS) through Week 52, the proportion of subjects who discontinued treatment because of adverse events was 1.8% in DUPIXENT 300 mg Q2W + TCS group and 7.6% in the placebo + TCS group

The feared side effects associated with cortisone treatment such as osteoporosis, weight gain, glaucoma, or mood changes are not to be expected when replacing cortisol in adrenal insufficiency

Dipeptidyl peptidase-4 (DPP-4) inhibitors, also known as gliptins, are used in the management of type 2 diabetes

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