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The mechanism by which GLP-1 receptor agonists might contribute to pancreatitis risk remains unclear, but possibilities include effects on pancreatic enzyme secretion, changes in gallbladder motility leading to gallstone formation, or direct effects on pancreatic tissue

Lastly, tirzepatide is also thought to work by slowing gastric emptying (the speed at which food moves through the digestive tract), causing you to feel fuller from your meals

A provider who evaluates you first and then recommends a medication based on clinical judgment is generally preferable to a model where you pick your drug and then get approval