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We postulated that if depletion of the UMP/UDP/UTP pool is driving this stress, then we would see similar effects with a DHODH inhibitor, BAY-2402234 (ref

Using macrophages, Lin et al

However, it would be interesting to see if similar bias occurs at central GLP-1r populations and whether this alters the synaptic and behavioral outcomes of GLP-1r agonism

Semaglutidewhether brand-name Ozempic or compounded formulationsis a temperature-sensitive injectable medication that loses effectiveness when exposed to improper storage conditions