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At Cape Fear Physical Medicine and Rehab, we offer GLP-1 receptor agonist medications to support your weight loss journey
The details of the search strategy are provided in Supplementary Table 1
Results announced in December 2025 confirmed the Phase 2 findings at a longer timepoint (Lilly Press Release, Dec 2025): The 28.7% weight loss at 68 weeks exceeds both semaglutide (~15% in STEP trials) and tirzepatide (~22.5% in SURMOUNT trials) at similar timepoints
How GLP-1 Meds Can Affect ADHD Meds Stimulants (Adderall, Vyvanse, Ritalin, Concerta, etc.) Appetite: You may notice even stronger appetite suppression
![In an earlier analysis of the SURMOUNT-1 trial, tirzepatide (a dual glucose-dependent insulinotropic polypeptide [GIP] and glucagon-like peptide-1 [GLP-1] receptor agonist) was shown to provide substantial and sustained reductions in body weight](https://lookaside.instagram.com/seo/google_widget/crawler/?media_id=3585945231426876830)
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