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Glossary CKD c hronic kidney disease CNS central nervous system CVD c ardiovascular disease FDA Food and Drug Administration GLP-1 glucagon-like peptide-1 GLP-1s glucagon-like peptide-1 receptor agonists HF Heart failure MASH metabolic dysfunction-associated steatohepatitis OA osteoarthritis OSA obstructive sleep apnea PAD peripheral arterial disease SC subcutaneous T2DM type 2 diabetes mellitus U.S

Prevention requires adequate protein intake, micronutrient optimisation (iron, zinc, vitamin D, B vitamins), and gradual weight loss of 0.51 kg weekly

Scientific References: StatPearls National Library of Medicine: Glucagon-Like Peptide-1 Receptor Agonists (Contraindications section) 4

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