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Our data further confirm the strong inhibitory effects of MT on NSCLC cells, consistent with previous studies [5, 7, 33]

For instance, decreased expression of lncRNA H19 increases ROS via the MAPK/ERK signaling pathway (Ding et al., 2018), while the reduction of lncRNA growth arrest specific 5 in melanoma enhances intracellular ROS (Chen et al., 2019)

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1 3 They may also have a variety of skeletal abnormalities including high arched palate, dental malpositions, cervical or cervicothoracic kyphosis, funnel chest, winged scapulae, spina bifida, hammer toes, bilateral pes cavus, and sacral dehiscence