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For Study 5, the primary efficacy parameter was mean percent change in body weight from randomization (Week 20) to Week 68

Among the cases of inappropriate PPI therapy, acute gastroenteritis was the most common diagnosis, accounting for 20.29% of unjustified PPI prescriptions

[DOI] [PMC free article] [PubMed] [Google Scholar] Le CC, Bennasroune A, Collin G, Hachet C, Lehrter V, Rioult D, Dedieu S, Morjani H, Appert-Collin A, 2020

The combination creates a dual-pathway stimulation: CJC-1295 (no DAC) amplifies GH production, while Ipamorelin triggers GH release, resulting in enhanced and sustained growth hormone elevation compared to single-peptide administration