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(34221552) Other mechanisms might include reduced calcium entry into neurons and enhanced GABA activity

Mitochondria and lysosomes are the organelle targets in the glucose-lowering effect of metformin

For example, cycle ergometer exercise (approximately 45% of maximum O 2 consumption for 90 min) increases the loss of creatine (as indicated by urinary creatinine excretion) by 52% above pre- and post-exercise values (Calles-Escandon et al