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Description

Due to intrinsic Cpf1 ribonuclease activity that facilitates crRNA processing and an array of donor DNA sequences for homology-directed repair of double-strand breaks generated by Cpf1, the multi-CRISPR/Cpf1 system is more efficient for multiplex deletion of up to four genes (Jimnez et al., 2019a)

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In this article, we'll delve into the mechanisms of these medications, potential benefits of combining them, and safety considerations

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