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They: Produce collagen Organize extracellular matrix Restore tensile structure In experimental tendon transection models, BPC-157 has been associated with: Increased fibroblast density Enhanced migration into injury site Accelerated granulation tissue formation Proposed signalling involvement includes: FAK (Focal Adhesion Kinase) activation ERK1/2 signalling Src pathway modulation FAK signalling is particularly important because it regulates: Cell adhesion Cytoskeletal reorganization Migration along collagen scaffolds Tendon strength depends not just on collagen quantity but alignment

Amycretin has been developed in both subcutaneous (once weekly) and oral (daily) formulations

Not full RCT publications

[17] The following table lists all GST enzymes of each class known to exist in Homo sapiens , as found in the UniProtKB/Swiss-Prot database