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In urology, Firmagon (degarelix) is a pure GnRH antagonist (as opposed to GnRH agonist like leuprolide) for prostate cancer, offering the clinical advantage of immediate testosterone suppression without the initial flare associated with GnRH agonists

These compounds function as enhancement tools rather than replacements for foundational practices

55 Likewise, data on mean BMI among HFrEF participants may not reflect the presence and severity of obesity as a target for the potential effectiveness of GLP-1 RAs

Pfizer acknowledged that the elevated liver enzymes observed in its trial were in line with rates seen in other approved GLP-1 medications