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At a time when morbidity and mortality of stroke, tumor, dementia and other neurodegenerative diseases are rising, and at a faster rate in low-to-middle income countries, access to BBB imaging - in both resource-rich and resource-limited settings - is imperative (Ezzati et al., 2018)

Precise incidence rates for bloating specifically are not comprehensively reported in tirzepatide clinical trials, as these symptoms may be captured under broader categories such as "abdominal distension," "dyspepsia," or "abdominal discomfort." However, gastrointestinal adverse events collectively affect a substantial proportion of patients receiving tirzepatide therapy

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