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Protects against enzymatic matrix degradation

Even though renal tissue is considered to be a major site for 1,25(OH)VD formation, recent studies demonstrate expression of ( CYP27B1 ) in nonrenal cells and tissues, indicating localized 1,25(OH) 2 VD formation and its tissue-specific paracrine function in different tissues (1)

Compared to apo-HTL7, MAX2-bound HTL7 clearly displays an additional density attached to the catalytic histidine H246 (Fig

The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine