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Table 8: Mean Changes in Anthropometry and Cardiometabolic Parameters in Study 1 (Patients without Diabetes) Table 9: Mean Changes in Anthropometry and Cardiometabolic Parameters in Study 2 (Patients with Diabetes Mellitus) Weight Management Trial In Pediatric Patients Ages 12 And Older With Obesity SAXENDA was evaluated in a 56-week, double-blind, randomized, parallel group, placebo controlled multi-center trial in 251 pubertal pediatric patients aged 12 to 17 years, with BMI corresponding to 30 kg/m or greater for adults by international cut-off points 1 and BMI of 95th percentile or greater for age and sex (NCT02918279)

Estradiol has been shown to impact this central CCK expression

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Peptide YY compounds and uses thereof as selective Y2 receptor agonists