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Urine mercury levels correlate with DNA methylation of imprinting gene H19 in the sperm of reproductive-aged men

Also published in the New England Journal of Medicine in 2022, the SURMOUNT-1 trial demonstrated that tirzepatide at the 15 mg dose produced an average weight loss of 22.5% of body weight over 72 weeks approaching results typically seen with bariatric surgery (Jastreboff et al., 2022, PMID: 35658024)

Aleksic, B., & Ozaki, N

If your total energy intake is low, your body prioritises using that energy for brain and vital organ functions, like your heart pumping blood around your body and your kidneys filtering waste and forming urine, as opposed to maintaining or building muscle