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The wave of launches marks a pivotal shift for Indias nascent GLP-1 market, where high prices had until now limited access despite surging global demand for the therapy

Earlier this year, Novo Nordisk said it would slash prices on its flagship medications in 2027 as it tries to win over customers

The proposed mechanism most often cited involves GIP-receptor-mediated effects on adipose insulin sensitivity and possibly on central energy balance, though attribution between the two receptors in vivo remains an area of ongoing study

The questions that Phase 3 will need to answer and that regulators will scrutinize closely include cardiovascular outcomes over extended periods, liver function changes beyond the 48-week window, potential interactions with other metabolic agents, and safety in populations not well-represented in Phase 2