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Since the Apollo-NADP + sensor response depends on the interaction (dimerization) of exogenous mutant G6PD tagged with a fluorescent protein, interactions between transfected and endogenous G6PD may reduce sensor response

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Gastrointestinal side effects led to treatment discontinuation in 10% of semaglutide patients versus 2% on placebo, though serious adverse events were actually less frequent with semaglutide (33.4% vs 36.4%)