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The selectivity of FOXO4-DRI for senescent over non-senescent cells is mechanistically grounded: FOXO4 is expressed at low levels in most non-senescent adult cells, but is strongly upregulated in senescent cells

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While the Daily Replenisher is free from many common allergens, individual sensitivities to specific ingredients like ashwagandha (which can affect thyroid function) or BioPerine (which can interact with certain medications) should be discussed with a healthcare provider

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