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However, high-dose L-carnitine therapy provides a massive amount of fuel for gut bacteria, causing them to produce more TMA than the livers FMO3 enzymes can process at one time [12] [13]

The quality of the weight loss

This oxidative stress is particularly damaging because of METHs effects on dopamine, which undergoes autoxidation, leading to the generation of dopamine quinones and ROS (Figure 1)