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Briefly, samples (10 L) were injected onto a Dionex RSLC U3000 LC system (Thermo) fitted with a ZIC-pHILIC column (5 m particle size, 4.6 by 150 mm

The complement pathway is also activated by Fc binding to the complement component C1q, resulting in the opsonization of viruses or infected cells and the recruitment of myeloid cells

These mice experienced significant improvements in body weight, colon length and disease symptoms

) Specifically, the changes to the gut microbiome composition caused a reduction in the intestinal cells that produce mucin, which is the barrier that prevents microbes from causing inflammation in the gut