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Description

These mitochondrial protein adducts are thought to cause mitochondrial dysfunction and to promote oxidant stress

Methods 298, 3344

Therefore, final level of ROS molecules could be highly dependent on involvement of many factors

When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations