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Combination biomaterial approaches: Researchers are exploring peptide-glycosaminoglycan hybrid hydrogels that combine the regenerative properties of peptides with the structural properties of the disc extracellular matrix

it is capable of playing the role of homeostatic regulator of synaptic changes in a broad variety of neuron types

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In contrast to the specific effects of GHRT by peptides directly within the GH neuroendocrine axis, GHS enhances secretory performance because it mitigates the progressive, maladaptive dominance of intrinsic factors such as sermorelin/GHRH and somatostatin (Figure 4)