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Because prostaglandins also help protect the stomach lining and support kidney function, long-term or high-dose use of NSAIDs can lead to side effects such as gastrointestinal ulcers, kidney strain, or increased cardiovascular risks

This is an excellent illustration of my current weekly video series on pharmacy benefit transparency

Barone JC, Ho A, Osborne LM, Eisenlohr-Moul TA, Morrow AL, Payne JL, Epperson CN, Hantsoo L (2024) Luteal phase sertraline treatment of premenstrual dysphoric disorder (PMDD): effects on markers of hypothalamic pituitary adrenal (HPA) axis activation and inflammation

These dietary changes alone may alter stool characteristics