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Dosages of 20 mg/day cRA were well tolerated, but severe toxicities were seen at 40 mg/day.54 Extremely high oral doses of RA (150 mg/m2 daily) showed no inhibitory effect on the activity of cisplatin and etoposide on small cell lung carcinoma in humans

The product cannot be used as a substitute for a varied diet

Inhibition of thioredoxin-reductase by auranofin as a pro-oxidant anticancer strategy for glioblastoma: In vitro and in vivo studies

Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies