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The role of hemovigilance and postmarketing studies when introducing innovation into transfusion medicine practice: the amotosalen-ultraviolet A pathogen reduction treatment model

In an uncontrolled trial in 100 men with infertility, a combination supplement containing 800 mg alpha-lipoic acid, 100 mg betaine, 400 mcg folic acid, 1,000 mg myo-inositol, 2.6 mg B12, 1.7 mg riboflavin, and 1.9 mg B6 was tested and reported to improve sperm concentration, motility, and morphology

And its not surprising that a deficiency can cause significant health issues

The product is intended for adults and should be used as directed