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[5] [19] Semaglutide works by mimicking the incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite

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While the link between Zepbound and NAION is continuing to be studied, it is believed it may result from fluctuations in blood pressure and blood sugar, which can affect blood flow to organs, diabetic-related vascular issues, hypoglycemia (low blood sugar), or potential side effects or interactions with other drugs, particularly those affecting blood pressure or vascular health