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Al emplear DMSO conviene mantener el porcentaje final del solvente en el medio celular por debajo de umbrales citotxicos y comparar siempre contra un control de vehculo equivalente

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These therapeutic options encompass RAS blockade, SGLT2 inhibition, GLP-1 receptor activation, endothelin-1 receptor blockade (atrasentan), vasopressin V2 receptor antagonism (tolvaptan), and selective mineralocorticoid receptor antagonism (finerenone), all demonstrating differential efficacy in retarding renal function decline (Huang et al., 2023)

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