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Common Degradation Pathways Deamidation of asparagine residues Methionine oxidation Peptide backbone hydrolysis Acyl chain hydrolysis Isomerization reactions Advanced LC-MS methods allow researchers to identify the exact location of degradation events within the peptide sequence

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The FDA has also raised concerns about unapproved GLP-1 products, and the World Health Organization has reported finding counterfeit versions of established GLP-1 medications in several countries, including the United States