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Injections can cause minor effects such as irritation or itching at the injection site, and the consumer fact sheet is a good plain-language reference on what B12 does and does not do

Medical Coding for Injections in 2026: CPT Codes, Administration Routes, Documentation Guidelines, and CPC Exam Tips By Janine Mothershed CPC, CPC-I Key Takeaways Injection administration coding depends on the route of administration , the drug or substance administered , and the medical necessity documented in the record

Once opened, a sterile water single-use vial should be used immediately and then thrown away any leftover is not saved

Vitamin B12 shots are completely safe, as any excess amount passes through the urine